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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ab652e83fedc88e67aab9d4282ca2e9cb29ca5a93003ff3a1ff098158895884' 
  AND token = 'Orv0LUMQQOsd88f8qAWzcnmL7WWvvOyxAWpq9KOwK7k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}