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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '03c957ce345a67ce4dcb7d3046118b76be5f7362d2bd188be586477286319e1c' 
  AND token = 'R3+bqybwg13T3StExry+usqKnnESd1eez4n1yAngCXg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}