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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f2c89599ffc3bfd2eabb0c13c342e450702677342ce32a66280866bf737dcb9' 
  AND token = 'Gr3lA4p/wo847LCfwkyLofRvl7F2EenyOHa7zOg9/Tk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}