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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '34a001e22aa1d7c18ffb82b105da1ecca6443a10c09e8ec0aaaaa3aa5bc9bf12' 
  AND token = 'Vq+/VYkLk/vOWDzT+c9qRReKMG9HUPnkWJZdS9f/Sqk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}