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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5d35d5b5c0afe26549ad05e4bb0fe10b31e37a77b2fc55d383e378227d90ee6' 
  AND token = 'S2Oa6yEy07sXtQwWQiTvozF2eWNRIDvnuSCbq3/YIQI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}