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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d5953d450ebceb008e7e55600c18084dce266a001ede1af942e26e09ce06d78' 
  AND token = 'VQD0F79g+eE0tTIH1A9b7BxDCsnkZrMNsfo1KVbD/fk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}