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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '008a28bd48c5cfbedea54f28c18b0c57d0875d5b27eb721d215838a3220776c7' 
  AND token = 'BM5T+IxzmUg/izmfy5NrznHn90e6F5iQcA5ecG+B1qc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}