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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd6105db261222e0850ff3569ce99c784e99834c3428bb604aedb9a6904180820' 
  AND token = '3KgIpH2tmHEToJLiEA+B+cVb8ShHlG91bCM+X01mw8I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}