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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b1c5cf6f787cb4fc5d4118d3d337211aa7a5e194612ce03e29848f44b23bdb7' 
  AND token = 'G+RsNNFrMAG62eDEd6F+Tx7ktqVINH9AyMg0EZ2HI94=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}