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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '630a368d10b7f24e4c9dc3f494fe4458c2e00adf65bd6d72fcde17c80121c8f9' 
  AND token = 'vDSBwatyesEk+N3uJ0FGOlbJ+UKEjaFBDGtB3fzXDWM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}