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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c4698d8f8bb6ab058b2f0bd39e5f8d3f9fc9fcf143de9d500e0140de22d6710' 
  AND token = 'tYE4dGuaSSkM4eLpRn72w2pduLh8Z+BURQoYAfoZmp4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}