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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5edfbc5d9677f0f31fd5aeb7bf719e8ec2aab720acf79a89ce5a024f7345043a' 
  AND token = 'B3E075ACykZuYW9LlOcijxB35o4uKf8LqSQEcAyzPnc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}