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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f43ef0222305f4a93c50de6d146c7e4dfcb1ea5ca3ee6261d17cb663fe115d1' 
  AND token = '9zmNBWCUxPSXEbpGiNQCnZuTOz/WLOmFunO1eqcEfi0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}