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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe2e33f24c5c5b415b75c488ef4f8a4b0377e366b0f7a7e459d4b564b82f58c0' 
  AND token = 'bm4M6y+3dbh4OMssMPEFHeJWDyDoD8lLisyBgI4wWUk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}