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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b4341e8f591215b6cb7f2b4bc1d24271a9a4a253e2be2034ea362c6d07d26dc' 
  AND token = 'JZane+FeW+mCntY/bMs6PoLKbGllwQi81lKN1kPcb/c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}