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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'afa51eadc07dba5613c3f09c3aaeb49750c8a5962c6957240976f36ccfffb959' 
  AND token = '6hIg7MTLrs6T5dvxZ9NvNqeSVVx7w7XV7HfCaqps/nI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}