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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25a684eb5749a2165f6cb9cf5329617bdc758aec0fb458d4f2dfa9fcfcc2e763' 
  AND token = 'jnfnIUuaK6wZUZSb4W3DWkMNDu3tN7Ao2xpWclyLcUI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}