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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '626b04eaeb3c428af1db5fca7ce1785e577410c0f9c8a7c7d2a635b6685cbe7a' 
  AND token = 'hVJmVX5qpyAhVHiuCA8k3AMEAylQ4JMBhFv4u8jMx1Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}