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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f04b1f2b55dfe4e52a5fccade3b6d64d1a08b29722cac1b9f922e8157c0c090' 
  AND token = 'hbC6GpGMqS8R2OnHhbGBfjsnXEMTxD66eFFP2nZXw2Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}