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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0dc4e8b84ff256b2ad8348f722878cbceb7dfe341dffa0b9120f77b238e9dff1' 
  AND token = 'KwE+7RluKqDWiqDyHXIR5kVgXPJxWdM14UgkwkCtjcM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}