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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de3cfda13d8461330f7bf8c8396550b9eb5985e50430d6990380f3a7de99ea1a' 
  AND token = 'EqwxBwM5+5c5xcXrHeK0mhG/vXxhCH2mv8uVmJaLUyk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}