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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f745d1a09c57e37db8fce440b5ac996dda49a69aa1c9a5b5683b126a169ea6f3' 
  AND token = 'sfqJY+oXTVs/rgtP6JFtQMPwZw9MalUkXNNFp7Z2Lwo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}