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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b86e297218e9e7eb9d7c370dd768dd6ce431bef26a0fa4fa07118bde8aaccf4' 
  AND token = 'LJmwWOXNVNnybNPlcmENqyz0avOPQfMvAJdM9SRcw50=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}