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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bc05f983db451c135f9cc2c3d097325fd0ac276c2d618cd833c40cd1ad3fbd07' 
  AND token = 'hJsxXElaS4rUs+2XMal22CGdTkDC4+qkNcm1GbUzEMM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}