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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33a327f2f3253d9fb04683a40d6a793c26699f77b3b1eac642c3403cb8c2bcb3' 
  AND token = '5V2//06U7/JVqRPqeQIkp+KBLG04D0h/MoVdZi7+qwE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}