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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2e4cbdd48ae705e31fa732a3ca095e3b1ad413b4ad127494d6e86e90270df66' 
  AND token = '/8MZ93/BRlJTH03T4FZV7UZoDTrGeNpOx5fp3M2LItQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}