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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8dabae2af31a1f1370248148b4266701feecf33ae35bbabdf0095d5b65f230fb' 
  AND token = 'GXqvpBl5OmyaTb/NLCwPl3j8Imm1wt6rmjMCWLSdmz8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}