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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '541c0c056112fa4e065881d8f3b35be7a2f55dae0b830e172d376685c524bb9a' 
  AND token = '2Knmd5XujIRmAFxd+LS8MeegaigYqmH8HRe+10WrvZs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}