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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88dfdde3bf18a19e702762a35c7f7f00e675d5a6c3ddca01c9f301d3216fa37f' 
  AND token = '7K9GArP2RkqfNWrDxs48NsLlUcYki/xq1KYPZHZGI3c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}