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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9cd5d4706de6d63e03bb048b51c4bb01e44162794aaec8357a1a60ac49de72e7' 
  AND token = '3S7Enaggha3KOaoJZFvor6FSj2crqBW5E3Ne8QsFnsw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}