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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb48dd64a4c85f6f48f20767f22a0bc8b9425c1bc5c2e70c8465c08e761a3ed4' 
  AND token = 'RiYIs/gTUevZmGQLY9b1ZBOUKJfub/pweWfoatrfP5M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}