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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '595d7a451f91f6e68194387a67695e2f83632c5c4e01cb41296b4552838e0150' 
  AND token = 'QyFSWPnFHwQOUL+/jLZTSFNr1NH96CsCFfGpZ4nLVM0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}