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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e87dcf8cb323870297cc00a85ec8beb1e9bc6f7612159f3794ed003f44b5cbe4' 
  AND token = 'Ok5K8QeYZ897y4C2UGFTjUhyb3xXHq6EwmUnOa1dvlo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}