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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd3eacb050f6f72177f49229e83671bbc78d5433081cf242da7eaf77476a6229b' 
  AND token = '7qFVXcSXodU3OG4pdmo6xFfGrNDB6mcfQuupOfRj2M0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}