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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e2bf29863acca7b8de2c05f176deb66b09aef9456ee75c6f07006fe903766aa' 
  AND token = 'eS9nrFmc+kuuauS7HMRJYmL4AaZ1wyd9ZlPwytezYiA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}