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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'efd8cbc965157f4fcd0ca0d746f7298e2b095d8fb708905964899af4a62c5135' 
  AND token = '5isikCuB+SBhWgw1iUVHKur3Tmrxt1HiGsw+LDIctW4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}