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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd70b5364b08ad2a8dec2efe626444bcaa7fea4ddb8cc27aee5a2343b411f6681' 
  AND token = 'cEYG3OokZXk/6hVuWpxAkP+oAOyQcX5xJqfWwqghuow=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}