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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '131660e9276d56fb5b88507ee446090c12898386f75804c3b63521952207dbb5' 
  AND token = 'E6XHQSAdaS1sNhzBoZc47/BDfbER/vR5JC18uzolRes=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}