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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8443c051745c061e941f4efd4a34b32a514a0beaab1c2a1d6c85db2b6b43828' 
  AND token = 'h6EVDquP2WSpb3Nmo5R3rUfKfhruRyBPQ3ogQ8+bIrE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}