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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6cb147da847e16ba606539ac155bcc2934bc274ae5023545f8a4c54aebe9218' 
  AND token = 'Gd50I0MO0CLwox+ETXkVbN7XPPOZg91D1yFLN/ARAYs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}