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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e52b28b824992d00a61630ab124048bec7ea06859b32ae79b2f8dcff4e9d09f9' 
  AND token = 'ZqHAzkmnV489wexI43hYzhPxdyNBkM4cnZei6MO+xII=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}