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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b070b6715702b556b945f7a3f106139b535d52d3019f34d646761d561b957ac0' 
  AND token = 'q5WCL2YIPJhcuzXaCqCgZdrq2VKCy0gm8cbNQF6uVg0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}