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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41c9a9b6c4fdeb5952f5197843020c1b514950a4e7ed538c01ba04e1d3bb7173' 
  AND token = 'zHC+QtiU1lKHlZBcOh9g07smyNrnl54TauZJDP4zTvY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}