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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef5788937c30ec574d5f70c6b4ba9048eb552ebd5c1498dff56b69d3f767f4bd' 
  AND token = 'nt70iFk3rJtYD3gxSdzPPV+VrSDVNFxkBkLSYCjoDDA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}