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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca954211290fe243844a1ca1540051d4346a88bd1969b542d2bb5df88ba43bd1' 
  AND token = 'fMIMfPY581RUOv+6h0uUsOg8ZgPk8wzKmJMqYhqNCZc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}