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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c24c7ecca47e656387971e7d22a909d260b7e9db2c358f1eb27172d39ca29bf' 
  AND token = 'yc5wxlFdHXoWD4kVUOWB3I4kNfQ52cMve9TmMf+cRdY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}