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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39444876c907f6a9c4eafee236e00db5faf7e3de7d90b4341cefeb4504a004dc' 
  AND token = 'CuW5Rv6cdlwhoqnPiI8OkxqefVuA7hbEfz61HIq0D0s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}