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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '55a117d0877e8f55daa8a06d00741129ecc599a967419b1bcf57a3a5d0508e42' 
  AND token = 'PA78g+4TwwhucmW+QhEE1hY0aCK/rYaG+eAp6dRM6Jg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}