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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dfa2a3b3d33a1274b1a3e31ced7883c57534764b1e70d1a368edfcc7b472def9' 
  AND token = 'E0wdi6w0YRlbL3oVBZU0TQ0Wg7WlsAR0TVm4xIBGpp4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}