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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '040c05015d15d43d3a08d23da5bb748e4537fd23e18020a4d90f3789253d0d38' 
  AND token = 'WSjtxc+yp0oXxClB0IMutd4kAF6WDRNLaloj05MexOk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}